Clathrate hydrates are ice-like compounds made up of crystalline cages of water molecules surrounding a guest species, including noble gases, low molecular weight gases, and small organic molecules. Hydrate particles form at low temperatures and high pressures and can cause risks to flow assurance of oil and gas pipelines by forming aggregates together. Thermodynamic inhibitors have been used in industry to reduce the hydrates’ effects but are costly to remove and may interfere with production policies. An alternate means of maintaining flow assurance can be achieved with low dosage inhibitors such as anti-agglomerates, which allow hydrates to form but not form aggregates. Along with prevention, it is key to be able to predict the behavior of gas hydrates.